منابع مشابه
Recombinant proteins in plants
Background Over the last few decades, several studies have shown that plants can be a viable option for producing functional recombinant proteins with a wide range of structural characteristics [1]. In addition, the potential benefit for developing countries is a prominent feature that we have recently addressed [2]. Plant-produced recombinant proteins can already be considered a novel componen...
متن کاملMetabolic Adaptation in Transplastomic Plants Massively Accumulating Recombinant Proteins
BACKGROUND Recombinant chloroplasts are endowed with an astonishing capacity to accumulate foreign proteins. However, knowledge about the impact on resident proteins of such high levels of recombinant protein accumulation is lacking. METHODOLOGY/PRINCIPAL FINDINGS Here we used proteomics to characterize tobacco (Nicotiana tabacum) plastid transformants massively accumulating a p-hydroxyphenyl...
متن کاملThe production of recombinant pharmaceutical proteins in plants.
Imagine a world in which any protein, either naturally occurring or designed by man, could be produced safely, inexpensively and in almost unlimited quantities using only simple nutrients, water and sunlight. This could one day become reality as we learn to harness the power of plants for the production of recombinant proteins on an agricultural scale. Molecular farming in plants has already pr...
متن کاملPlants as factories for the Production of Pharmaceutical recombinant proteins
Nowadays, transgenic plants are used as an attractive alternative to produce recombinant pharmaceutical proteins. Recombinant proteins such as vaccines and antibodies can be produced in plants via two systemes: stable genetic transformation and transient expression. Stable transformation is included of integrating a gene into the plant nuclear or chloroplast genome. The transient expression can...
متن کاملRecombinant Cytokines from Plants
Plant-based platforms have been successfully applied for the last two decades for the efficient production of pharmaceutical proteins. The number of commercialized products biomanufactured in plants is, however, rather discouraging. Cytokines are small glycosylated polypeptides used in the treatment of cancer, immune disorders and various other related diseases. Because the clinical use of cyto...
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ژورنال
عنوان ژورنال: Methods in molecular biology
سال: 2022
ISSN: ['1940-6029', '1064-3745']
DOI: https://doi.org/10.1007/978-1-0716-2241-4